Category Archives: ML in Practice

Logistic regression: moving from significant results to meaningful insight

Association studies are a favourite tool for geneticists to understand the genetics that determine our health. It is simply routine now to test every mutation amongst your patients for association with a given trait (for example BMI or breast cancer).

Logistic regression: moving from significant results to meaningful insight

Association studies are a favourite tool for geneticists to understand the genetics that determine our health. It is simply routine now to test every mutation amongst your patients for association with a given trait (for example BMI or breast cancer).

Clustering Gene Expression Data: adding layers to a heatmap

So you have some data, perhaps a lot of data, but you’re not quite sure what to do with it… where do you start? Is it interesting data? Would it tell a good story, or just be a confusing mess?  This

Clustering Gene Expression Data: adding layers to a heatmap

So you have some data, perhaps a lot of data, but you’re not quite sure what to do with it… where do you start? Is it interesting data? Would it tell a good story, or just be a confusing mess?  This

SQL vs. BioMart for querying the human genome

A huge part of my job is to add context and build layers of information on top of the genetic mutation datasets that we have amongst our groups. If we want to understand the importance of genetic mutations on human

SQL vs. BioMart for querying the human genome

A huge part of my job is to add context and build layers of information on top of the genetic mutation datasets that we have amongst our groups. If we want to understand the importance of genetic mutations on human

Clustering techniques for variant calling

The verification of variant calling is both subjective and time-consuming. Whilst Genome Studio is able to automatically determine genotype from Illumina sequencing chips, the quality of these clustering predictions can be highly variable, which necessitates visual confirmation and adjustment. When considering

Clustering techniques for variant calling

The verification of variant calling is both subjective and time-consuming. Whilst Genome Studio is able to automatically determine genotype from Illumina sequencing chips, the quality of these clustering predictions can be highly variable, which necessitates visual confirmation and adjustment. When considering

Heat Stress Indicators & Climate Change: Exploring the relaxation of Wet Bulb Temperature

Ever since the early 2000s climate change has been big news. John Sutter of CNN (2015) recently quoted Gina McCarthy (Environmental Protection Agency, USA) stating that “climate change is the greatest threat of our time”. The effects of climate change

Heat Stress Indicators & Climate Change: Exploring the relaxation of Wet Bulb Temperature

Ever since the early 2000s climate change has been big news. John Sutter of CNN (2015) recently quoted Gina McCarthy (Environmental Protection Agency, USA) stating that “climate change is the greatest threat of our time”. The effects of climate change

Be wary of predictions, they might not be as accurate as you thought…

The two terms prediction and accuracy are always considered hand-in-hand. For example, if we want to predict the presence of cancer in a patient, that prediction had better be accurate! In the commercial world we might be interested in predicted

Be wary of predictions, they might not be as accurate as you thought…

The two terms prediction and accuracy are always considered hand-in-hand. For example, if we want to predict the presence of cancer in a patient, that prediction had better be accurate! In the commercial world we might be interested in predicted

Exploring & Extending IBM’s SlamTracker

The 2015 Australian Open was a fantastic event! From the Australian perspective, it was encouraging to see so many Australian players winning deep into the event. And Djokovic was a class act, he appeared to be in complete control, dug

Exploring & Extending IBM’s SlamTracker

The 2015 Australian Open was a fantastic event! From the Australian perspective, it was encouraging to see so many Australian players winning deep into the event. And Djokovic was a class act, he appeared to be in complete control, dug